By P. K. Ray
The fast and non-stop upsurge of fascinating info within the topic of tumor immunology necessitates the e-book of an annual sequence to provide the up-to-date fabrics to the scholars, researchers, and clinicians during this swiftly advancing box. suggestions and methodologies are ever altering. additionally, present study in tumor immunology can provide to provide breakthroughs sooner or later. vital is the necessity to converse to the precise humans the precise position of immunodiagnostic equipment and immunolog ical intervention in melanoma prevention and remedy. The position of immuno treatment together with traditional modalities of remedy wishes in its right viewpoint. Oncogene, interferon, lympho to be understood kines, monoclonal antibodies, usual killer cells, platelet-mediated cyto toxicity of antibody-coated goal cells, suppressor cells, platelet-derived components, plasma-blocking components, keep an eye on of suppressor phone functionality, ab rogation of plasma-blocking elements, and so on. , are a number of the parts which are regularly advancing. development in those parts could have implication in melanoma treatment. extra, it really is already understood that if immunocompe tence of the host could be maintained at a fairly solid point, there exists the aptitude to extend the healing indexes of traditional modalities of remedy. This sequence will try and current up-to-date infor mation in a lot of these parts in line with contributed and solicited articles. P. K.
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Additional info for Advances in Immunity and Cancer Therapy: Volume 1
Clin. lmmllnol. 7:139,1982. Cells Responsible for Tumor Surveillance in Man 27 102a. : J. Clin. Lab. Immunol. II :33, 1983. 103. : Aeta Radiol. 13:83, 1974. 104. : Int. J. Radiat. Oneol. BioI. Phys. 2:289, 1977. 105. : Int. J. Radiat. Oneol. BioI. Phys. 6:471, 1980. 106. : Int. 1. Radiat. On col. BioI. Phys. 5:49, 1979. 107. : Clin. Exp. Immunol. 38:366, 1979. 108. : Int. 1. Radiat. Oncol. BioI. Phys. 4:249, 1978. 109. : Anticancer Research 2:209, 1982. 110. : Radiother. Oncology, 1:255, 1984. Ill.
This leads us to an important and controversial issue, that of using RT as an adjuvant to surgical resection of tumor. A collaborative study to find the efficacy of preoperative irradiation of cancer of the lung had disappointing results (164). It may be that the immunosuppressive effects of RT cancel the potential benefits of this treatment. This seems plausible, as immune response against lung cancer is well known (165). The removal or elimination of regional lymph nodes (RLN) in radical mastectomy for breast cancer has received wide attention.
Recovery of the Immune System Following RT. . .... Immune Status of Patients Receiving RT. . . . . . . . . . . . Potentiation of Antitumor Immune Response During RT for Cancer Patients. . . . . . . . . . . . . . . . . . . . . Potentiation of Antitumor Immune Response by RT in Experimental Models. . . . . . . . . . . . . . . . . . Immunologic Component in RT-Induced Tumor Cure. . . . . RT-Induced Immunosuppression.
Advances in Immunity and Cancer Therapy: Volume 1 by P. K. Ray