Download e-book for iPad: Cancer-Associated Thrombosis: New Findings in Translational by Alok A. Khorana, Charles W. Francis

By Alok A. Khorana, Charles W. Francis

ISBN-10: 142004799X

ISBN-13: 9781420047998

Showcasing the services of top-tier experts who contributed to the newly published instructions for the care of thrombosis in melanoma sufferers, this intriguing consultant used to be written and edited by means of individuals of the yank Society of medical Oncology panel, (ASCO), at the prevention and therapy of cancer-associated thrombosis, between others, and gives an authoritative dialogue of concepts to successfully enforce and interpret the recent ASCO/NCCN directives. status because the in simple terms up to date resource to easily learn intriguing new translational technological know-how findings concerning the biology of cancer-associated thrombosis, in addition to new medical innovations, this advisor offers an authoritative and present dialogue of the mechanisms, administration, and prevention of cancer-associated thrombosis.

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Extra info for Cancer-Associated Thrombosis: New Findings in Translational Science, Prevention, and Treatment

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Wang X, Gjernes E, Prydz H. Factor VIIa induces tissue factor-dependent up-regulation of Interleukin-8 in a human keratinocyte line. J Biol Chem 2002; 277:23620–23626. 55. Hjortoe GM, Petersen LC, Albrektsen T, et al. Tissue factor-factor VIIa specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated via PAR-2 and results in increased cell migration. Blood 2004; 103(8):3029–3037. 56. Liu Y, Mueller BM. Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways.

Ruf W, Mueller BM. Thrombin generation and the pathogenesis of cancer. Semin Thromb Hemost 2006; 32(suppl 1):61–68. 64. Belting M, Dorrell MI, Sandgren S, et al. Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med 2004; 10(5):502–509. 65. Versteeg HH, Spek CA, Richel DJ, Peppelenbosch MP. Coagulation factors VIIa and Xa inhibit apoptosis and anoikis. Oncogene 2004; 23(2):410–417. 66. Hu L, Lee M, Campbell W, Perez-Soler R, Karpatkin S. Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis.

Wang H, Fu W, Im JH, et al. Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. J Cell Biol 2004; 164(6):935–941. 52. Koizume S, Jin M-S, Miyagi E, et al. Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res 2006; 66(19):9453–9460. 53. Riewald M, Ruf W. Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci USA 2001; 98:7742–7747. 54. Wang X, Gjernes E, Prydz H.

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Cancer-Associated Thrombosis: New Findings in Translational Science, Prevention, and Treatment by Alok A. Khorana, Charles W. Francis

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