By H. Oberpichler-Schwenk (auth.), Prof. Dr. S. Hoyer, Dr. D. Müller, Dr. K. Plaschke (eds.)
ISBN-10: 3211825495
ISBN-13: 9783211825495
ISBN-10: 3709193508
ISBN-13: 9783709193501
Although age has been well-known as a threat issue for late-onset dementia of Alzheimer sort, its etiology is unknown as but. a number of age-related metabolic abnormalities may perhaps hence turn into very important for the pathogenesis of the late-onset shape. reports on the cellular/molecular point in mind tissue are attainable submit mortem, yet lack details at the starting of the illness. during this complement, diverse methods are handled how you can set off structural and/or metabolic abnormalities in appropriate cellphone cultures, in mind slices and in experimental animals, and the way behavioral adjustments parallel the metabolic variations.
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Additional info for Cell and Animal Models in Aging and Dementia Research
Example text
Proc Natl Acad Sci USA 85: 9811-9815 Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L (1992) A pathogenic mutation of probable Alzheimer's disease in the APP gene at the N-terminus of ~-amyloid. Nature Genet 1: 345-347 Murrell J, Farlow M, Ghetti B, Benson MD (1991) A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 254: 97-99 Nakamura K, Wu G, Ledeen RW (1992) Protection of neuro-2a cells against calcium ionophore cytotoxicity by gangliosides.
1 Neurosci Res 25: 360-368 10hnson GV, Litersky 1M, lope RS (1991) Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study. 1 Neurochem 56: 1630-1638 Kalaria RN, Harik SI (1989) Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer's disease. 1 Neurochem 53: 1083-1088 Kang 1, Lemaire H-G, Unterbeck A, Salbaum 1M, Masters CL, Grzesckik K-H, Multhaup G, Beyreuther K, Muller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
From the Kentucky Research Foundation. References Abe K, Tanzi RE, Kogure K (1991) Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex. Neurosci Lett 125: 172-174 Andorn AC, Britton RS, Bacon RR (1990) Evidence that lipid peroxidation and total iron are increased in Alzheimer's brain. Neurobiol Aging 11: 316 40 V. L. Smith-Swintosky and M. P. Mattson Araki W, Kitaguchi N, Tokushima Y, Ishii K, Aratake H, Shimohana S, Nakamura S, Kimura J (1991) Trophic effects of ~-amyloid precursor protein on cerebral cortical neurons in culture.
Cell and Animal Models in Aging and Dementia Research by H. Oberpichler-Schwenk (auth.), Prof. Dr. S. Hoyer, Dr. D. Müller, Dr. K. Plaschke (eds.)
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